周晗，博士，副研究员

电话：0411-84379539

邮箱：zhouhan418@dicp.ac.cn

个人主页网址：https://people.ucas.edu.cn/~zhouhan

工作经历：

1）2019-05~2020-06,Columbia University, 访问学者
2）2018-06~现在, 中国科学院大连化学物理研究所, 副研究员
3）2016-09~2018-06,中国科学院大连化学物理研究所, 助理研究员
4）2014-02~2016-06,Northeastern University, 博士后

教育经历：

1）2007-09--2014-01   Northeastern University   研究生学历 博士学位
2）2003-09--2007-07   中国科学技术大学 本科学历 学士学位

研究方向：

1）中药大数据与人工智能

2）计算生物学与生物信息学

3）蛋白结合口袋与复合物预测

代表性成果：

1. Qinghua Yu, Xiaomin Xie, Hongming Tang, Yuqian Wang, Yunpeng Wu, Ruogu Zhang, Qi Gao, Zhixin Guo, Shigen Ye, Han Zhou*, Weijia Zhou*, Inhibitory effects of esculetin as a quorum sensing inhibitor on biofilm formation and virulence factors in Vibrio anguillarum, World Journal of Microbiology and Biotechnology, 2026, 42:264

2. Han Zhou, Tao Hou, Aijin Shen, Wenyi Yu, Liangliang Zhou, Wenjie Yuan, Wanxian Wang, Yumin Yao, Jixia Wang*, Yanfang Liu*, Xinmiao Liang, Elucidation of active components and target mechanism in Jinqiancao granules for the treatment of prostatitis and benign prostatic hyperplasia, Journal of Ethnopharmacology, 2024, 328, 118068

3. Xiufang Chen, Han Zhou*, Tao Hou, Jinli Lu, Jun Wang, Liangliang Zhou, Yaopeng Zhao, Yanfang Liu, Jixia Wang, Xinmiao Liang, Chan Chen*, The dual-targeting mechanism of an anti-inflammatory diarylheptanoid from Curcuma zedoaria (Christm.) Roscoe with the capacity for β2-adrenoreceptor agonism and NLRP3 inhibition, Chemico-Biological Interactions, 2023, 386, 110771

4. Han Zhou, Tao Hou, Zhenhua Gao, Xiujie Guo, Chaoran Wang, Jixia Wang*, Yanfang Liu, Xinmiao Liang, Discovery of eight alkaloids with D1 and D2 antagonist activity in leaves of Nelumbo nucifera Gaertn. Using FLIPR assays, Journal of Ethnopharmacology, 2021, 278, 114335

5. Han Zhou, Xingrong Peng, Tao Hou, Nan Zhao, Minghua Qiu, Xiuli Zhang*, Xinmiao Liang, Identification of novel phytocannabinoids from Ganoderma by label-free dynamic mass redistribution assay, Journal of ethnopharmacology, 2020, 246, 112218

6. Han Zhou, Yan Peng, Aneetha Halikhedkar, Pusheng Fan, David R Janero, Ganesh A Thakur, Richard W Mercier, Xin Sun, Xiaoyu Ma, Alexandros Makriyannis*, Human cannabinoid receptor 2 ligand-interaction motif: Transmembrane helix 2 cysteine, C2. 59 (89), as determinant of classical cannabinoid agonist activity and binding pose, ACS Chemical Neuroscience, 2017, 8 (6), 1338-1347

7. 刘凡; 周晗; 周亮亮; 刘格锋; 李潇逸; GPCR结合位点数据库系统 [简称：GPCR-BSD] V1.0,2024SR2119190, 原始取得, 全部权利, 2024-12-18 (软件著作权)

8. 梁鑫淼; 侯滔; 彭惺蓉; 邱明华; 张秀莉; 周晗; 王纪霞; 徐芳芳; 化合物作为或在制备阿片受体拮抗剂中的应用和药物组合物, 2023-06-06, 中国, ZL 2020 1 1413848.9 (授权专利)

9. 梁鑫淼; 侯滔; 彭惺蓉; 邱明华; 张秀莉; 周晗; 王纪霞; 徐芳芳; 药物组合物及化合物作为或在制备阿片受体拮抗剂中的应用, 2023-06-06, 中国, ZL 2020 1 1404474.4 (授权专利)