董雪芳，博士，副研究员
本草物质科学研究室/中药科学研究中心
电话：0411-84379541
邮箱：dongxuefang@dicp.ac.cn
学习和工作经历：
2006.9~2010.7 沈阳药科大学 生物制药专业 获工学学士学位
2010.9~2016.6 中科院大连化学物理研究所 分析化学专业 获理学博士学位
2016.7~2021.6 中科院大连化学物理研究所 助理研究员
2021.7~至今 中科院大连化学物理研究所 副研究员
研究方向：
翻译后修饰蛋白组学新材料与新方法、药物蛋白组学
代表性成果：
1. Dong Xuefang; Xiong Fangfang; Du Guangzhu; Yang Yunfei; Chen Cheng; Cui Yun; Ding Xinlian; Li Xiuling; Shen Yidong; Liang Xinmiao; A versatile platform for sequential glyco-, phospho-, and proteomics with multi-PTMs integration. Nature Communications, 2026, 17: 948. （共同一作）
2. Song Yongyang; Dong Xuefang; Shang Danyi; Zhang Xiaofei; Li Xiuling; Liang Xinmiao; Wang Shutao; Unusual Nanofractal Microparticles for Rapid Protein Capture and Release. Small, 2021, 17. （共同一作）
3. Dong Xuefang; Chen Cheng; Yan Jingyu; Zhang Xiaofei; Li Xiuling; Liang Xinmiao; Comprehensive O-Glycosylation Analysis of the SARS-CoV-2 Spike Protein with Biomimetic Trp-Arg Materials. Analytical Chemistry, 2021, 93: 10444-10452. （第一作者）
4. Dong Xuefang; Shi Jingchen; Zhao Yanyan; Zhao Liang; Li Xiuling; Liang Xinmiao; Dual Protease-Mediated Proteolysis Coupled with Ultrafiltration for System-Level Profiling of Drug Targets and Conformational Dynamics. Analytical Chemistry, 2026, 98: 2116-2128. （共同一作）
5. Dong Xuefang; Qin Hongqiang; Mao Jiawei; Yu Dongping; Li Xiuling; Shen Aijin; Yan Jingyu; Yu Long; Guo Zhimou; Ye Mingliang; Zou Hanfa; Liang Xinmiao; In-Depth Analysis of Glycoprotein Sialylation in Serum Using a Dual-Functional Material with Superior Hydrophilicity and Switchable Surface Charge. Analytical Chemistry, 2017, 89: 3966-3972. （共同一作）
6. Dong Xuefang; Li Xiuling; Chen Cheng; Zhang Xiaofei; Liang Xinmiao; Systematic analysis and comparison of O-glycosylation of five recombinant spike proteins in 8-coronaviruses. Analytica Chimica Acta, 2022, 1230. （第一作者）
7. Du Guangzhu; Chen Cheng; Cui Yun; Huang Beibei; Zheng Yi; Yan Jingyu; Shang Danyi; Dong Xuefang; Jin Meihua; Li Xiuling; Glycosylation profiling of monkeypox virus structural proteins with poly Ser-Arg materials. Analyst, 2025, 150: 680-691. （通讯作者）
8. Dong Xuefang; Ding Xinlian; Yuan Lingyan; Cui Yun; Bing Zhitong; Yu Long; Yang Lei; Li Xiuling; Liang Xinmiao; Deciphering radiopharmaceutical mechanisms through integrated proteomic and PTM-proteomic profiling. Analyst, 2025, 150: 3946-3957. （共同一作）
9. Li Juan; Dong Xue-fang; Cui Yun; Liang Xinmiao; Li Xiu-ling; Application of the YD dipeptide polymer for simultaneous phosphopeptide and O-glycopeptide capture. Microchemical Journal, 2026, 220. （共同一作）
10. Xiao Yanwei; Dong Xuefang; Chen Cheng; Cui Yun; Chu Tongbin; Li Xiuling; Wang Aoxue; An integrated method for IgG N-glycans enrichment and analysis: Understanding the role of IgG glycosylation in diabetic foot ulcer. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 2024, 1233. （共同一作）
