欢迎访问中国科学院大连化物所中药科学研究中心网站!

学术成果
发表论文
时间:2020-10-21       栏目类别:学术成果

16.Chunying Song, Dongping Yu, Gaowa Jin, Yongzheng Zhou, Ziwei Han, Han Zhou, Liduo Huo, Lijie Liu, Zhimou Guo, Xinmiao Liang, Synthesis and Chromatographic Evaluation of Perfluorooctyl Stationary Phase for Separation of Basic Compounds,Chromatographia, 2022, 85, 447–454. 项目编号: This work was financially supported by the National Key Research and Development Program of China (2016YFB0301502) and the National Natural Science Foundation of China (22074141). 关键词 : Fluorinated stationary phases, High-performance liquid chromatography, Basic compounds, Stationary phases, Traditional Chinese medicine.

17.Chunying Song, Dongping Yu, Gaowa Jin, Junjie Ding, Han Zhou, Zhimou Guo, Xinmiao Liang, High-performance liquid chromatography quantitative analysis of ephedrine alkaloids in Ephedrae Herba on a perfluorooctyl stationary phase, Journal of Separation Science, 2022, 45(5), 1051–1058. 项目编号: This work was financially supported by the National Key Research and Development Program of China (2016YFB0301502) and the National Natural Science Foundation of China (22074141). 关键词: ephedrine alkaloids, high performance liquid chromatography, perfluorooctyl stationary phase, quantitative analysis.

18.Wang Pan, Peng Xingrong, Hou Tao, Xu Fangfang, Zhou Han, Yu Yancheng, Qiu Minghua, Liu Yanfang, Zhao Yaopeng, Guo Zhimou, Wang Jixia, Liang Xinmiao, Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay,Chemico-Biological Interactions, 2022, 367, 110199(1-8). 项目编号: This work was supported by “Project of National Natural Science Foundation of China (82173962)”, Liaoning Province “Xingliao Talent Program” Project (XLYC1908035) and the innovation program of science and research from DICP, CAS (DICP, CAS018). 关键词:ACLY inhibitor, High-throughput screening, Natural products, Inhibition profiles.

19.Wang Pan, Hou Tao, Xu Fangfang, Luo Fengbin, Zhou Han, Liu Fan, Xie Xiaomin, Liu Yanfang, Wang Jixia, Guo Zhimou, Liang Xinmiao, Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase: Structure-Activity Relationship and Inhibition Profiles,International Journal of Molecular Sciences, 2022, 23(18), 10747(1-14). 项目编号: This work was supported by “Project of National Natural Science Foundation of China (82173962)” and the innovation program of science and research from DICP, CAS (DICP I202018) and Jiangxi “Double Thousand Plan”. 关键词: ACLY inhibitor; flavonoid; structure–activity relationship; herbacetin.

20.HongLi Wei, YaoPeng Zhao, JiXia Wang, Yang Han, Hao Li, Han Zhou, Tao Hou,ChangJian Wang, YuMin Yao, XiuLi Zhang, YanFang Liu, XinMiao Liang, Menisperdaurines A-W, structurally diverse isoquinoline alkaloids from Menispermum dauricum and their dopamine D1 receptor activities,Bioorganic Chemistry, 2022, 127, 106027(1-12). 项目编号: DICP ZZBS201803.关键词: Menispermum dauricum DC., Menispermaceae, Isoquinoline alkaloids, Electronic circular dichroism, D1 antagonistic activity.

21.Xiang Kaijing, Zhou Weijia, Hou Tao, Yu Long, Zhou Han, Zhou Liangliang, Liu Yanfang, Wang Jixia, Guo Zhimou, Liang Xinmiao, Integration of Two-Dimensional Liquid Chromatography-Mass Spectrometry and Molecular Docking to Characterize and Predict Polar Active Compounds in Curcuma kwangsiensis, MOLECULES, 2022, 27(22), 7715(1-16). 项目编号: the Project of National Natural Science Foundation of China (81803706), Liaoning Province “Xingliao Talent Program” Project (XLYC1908035), Foundation of Liaoning Educational Committee (100920202027) and Liaoning Province “Doctoral Scientific Research Foundation” Project (2021-BS-236). 关键词: Curcuma kwangsiensis; polar compounds; reversed-phase liquid chromatography hydrophilic interaction chromatography; quadrupole time-of-flight mass spectrometry; molecular docking.

22.Xu Yang, Wang Rong, Hou Tao, Li Hao, Han Yang, Li Yan, Xu Linli, Lu Shubin, Liu Lei, Cheng Junxiang, Wang Jixia, Xu Qing, Liu Yanfang, Liang Xinmiao, Uncariphyllin A-J, indole alkaloids from Uncaria rhynchophylla as antagonists of dopamine D2 and Mu opioid receptors,BIOORGANIC CHEMISTRY, 2023, 130,106257.

23.Yu Wenyi, Fu Cai, Zhou Han, Liu Guoqiang, Zheng Jinlei, Liu Hongjiang, Li Meng, Shen Aijin, Liu Yanfang, Liang Xinmiao, Integrated strategy for identifying isoflavones in Belamcandae Rhizoma based on the combination of mass defect filtering and neutral-loss-triggered multistage fragmentation, JOURNAL OF CHROMATOGRAPHY A, 2022, 1679, 463379(1-8). 项目编号: National Key R&D Program of China ( 2020YFC0845400 ) and Jiangxi “Double Thousand Plan ”( 2019 and 2020 ). 关键词: Belamcandae Rhizoma Isoflavones Mass defect filtering (MDF) Neutral-loss-triggered multistage fragmentation (NLT-MS n ) High resolution multistage mass spectrometry.

24.余文怡, 应金琴, 刘艳芳, 徐青, 沈爱金, 梁鑫淼, 诊断离子技术在中药质谱分析中的应用,分析测试学报, 2022, 41(09), 1419-1430. 项目编号: 辽宁省“兴辽英才计划”项目(XLYC1908035);江西省“双千计划”项目. 关键词: 诊断离子;中药质谱分析;化学成分鉴定.

25.Xiaotao Yang, Xiaofei Zhang, Yulong Li, Xiuling Li, Xinmiao Liang, Ye Tian, Lei Jiang, TiO2 with Confined Water Boosts Ultrahigh Selective Enrichment of Phosphorylated Proteins,ACS Applied Materials & Interfaces, 2022, 14(16), 19067−19075. 项目编号: The authors thank the financial support by the National Research Fund for Fundamental Key Projects of China (2017YFA0204504, 2018YFA0208502), National Natural Science Foundation (21934005, 21974135, 21972154, 21988102, 22090052), Frontier Science Key Projects of CAS (ZDBS-LY-SLH022), and Dalian Institute of Chemical Physics Innovation Funding (DICP I202030, DICP I202114). 关 键 词 : TiO2, superhydrophilic, phosphorylated proteins, selective enrichment, confined water.

26.Xu Y, Liu Y, Zhou H, Wang R, Yu D, Guo Z, Liang X. A guide of column selection for two-dimensional liquid chromatography method development of natural alkaloids. Talanta. 2023 Jan 1;251:123738.

27.Zhang C, Liu Z, Lu S, Xiao L, Xue Q, Jin H, Gan J, Li X, Liu Y, Liang X. Rapid Discrimination and Prediction of Ginsengs from Three Origins Based on UHPLC-Q-TOF-MS Combined with SVM. Molecules. 2022 Jun 30;27(13):4225.

28.Dong X, Li X, Chen C, Zhang X, Liang X. Systematic analysis and comparison of O-glycosylation of five recombinant spike proteins in β-coronaviruses. Anal Chim Acta. 2022 Oct 16;1230:340394.

29.Han Y, Hou T, Zhang ZH, Wang YD, Cheng JX, Zhou H, Wang JX, Feng JT, Liu YF, Guo ZM, Liang XM. Structurally diverse isoquinoline and amide alkaloids with dopamine D2 receptor antagonism from Corydalis bungeana. Fitoterapia. 2022 Jun;159:105175.

30.Jiang H, Hou T, Han Y, Lu SB, Liu L, Li DX, Zhu YH, Huang H, Li WJ, Xue XY, Liu YF, Liang XM. Preparation and identification of isoquinoline alkaloids with ATP citrate lyase inhibitory activity from Dactylicapnos scandens. Fitoterapia. 2023 Mar;165:105397.

上一页 [1] [2] [3] [4] [5] [6] [7] 下一页

版权所有 © 中国科学院大连化学物理研究所  本草物质科学研究室  中药科学研究中心  辽ICP备05000861号

地址:辽宁省大连市沙河口区中山路457号  邮政编码:116023