梁鑫淼，博士，研究员/室主任
本草物质科学研究室/中药科学研究中心
电话：0411-84379519
邮箱：liangxm@dicp.ac.cn
学习和工作经历：
2007.09－今 中科院大连化学物理研究所 二级研究员
1995.08－2007.12 中科院大连化学物理研究所 研究员
1994.05－1994.12 德国环境与健康研究中心生态化学研究所合作研究
1993.04－1995.08 中科院大连化学物理研究所 副研究员
1992.12－1993.04 中科院大连化学物理研究所 助理研究员
1987.09－1992.12 中科院大连化学物理研究所 博士生
1983.09－1987.07 杭州大学化学系 本科生
研究方向：
主要从事色谱理论基础、新型分离材料合成、中药系统分离与表征研究、新药开发等。
代表性成果：
1、Dongping Yu, AijinShen, Zhimou Guo*, Yukun Yan, Jingyu Yan, Gaowa Jin, Xinmiao Liang*; A controlled thiol-initiated surface polymerization strategy for the preparation of hydrophilic polymer stationary phases; Chemical Communications;6, 85842015, 51 (79): 14778-14780.
2、Tao Hou, Liying Shi, Jixia Wang, Lai Wei, Lala Qu, Xiuli Zhang*, Xinmiao Liang*, Label-free cell phenotypic profiling and pathway deconvolution of neurotensin receptor-1, Pharmacological Research,2016, 108: 39-45.
3、Lai Wei, Jixia Wang, Xiuli Zhang*, Ping Wang, Yaopeng Zhao, Jiaqi Li, Tao Hou, Lala Qu, Liying Shi, Xinmiao Liang*, and Ye Fang*, Discovery of 2H-Chromen-2-one Derivatives as G Protein-Coupled Receptor-35 Agonists. Journalof Medicinal Chemistry.2017,60(1): 362-372.
4、Guangyan Qing, Qi Lu, Xiuling Li*, Jing Liu, Mingliang Ye, Xinmiao Liang*, Taolei Sun*, Hydrogen bond based smart polymer for highly selective and tunable capture of multiply phosphorylated peptides, Nature Communications,2017,8: 461,DOI:
5、Zhou Weijia, Wang Jixia, Zhao Yaopeng, Yu Long, Fang Ye, Jin Hongli, Zhou Han, Zhang Pengyu, Liu Yanfang*, Zhang Xiuli*, Liang Xinmiao*, Discovery of beta2- adrenoceptor agonists in Curcuma zedoaria Rosc using label-free cell phenotypic assay combined with two-dimensional liquid chromatography, Journal of chromatography. A,2018, 1577 , 59-65.
6、Song Yongyang, Li Xiuling, Fan Jun-Bing, Kang Hongjian, Zhang Xiaofei, Chen Cheng, Liang Xinmiao*, Wang Shutao*,Interfacially Polymerized Particles with Heterostructured Nanopores for Glycopeptide Separation,ADVANCED MATERIALS,2018,30(39),1803299(1-8).
7、Zhou Weijia, Guo Zhimou, Yu Long, Zhou Han, Shen Aijin, Yan Jin, Jin Gaowa, Yan Jingyu, Yang Fan, Liu Yanming, Wang ChaoRan, Feng JiaTao, Liu Yanfang*, Liang Xinmiao*, On-line comprehensive two-dimensional liquid chromatography tandem mass spectrometry for the analysis of Curcuma kwangsiensis, TALANTA,2018, 186,73-79.
8、Jingyu Yan, Junjie Ding, Gaowa Jin, Zhaojun Duan, Fan Yang, Dandi Li, Han Zhou, Ming Li, Zhimou Guo*, Wengang Chai, Xinmiao Liang*, Profiling of Human Milk Oligosaccharides for Lewis Epitopes andSecretor Status by Electrostatic Repulsion Hydrophilic InteractionChromatography Coupled with Negative-Ion Electrospray TandemMass Spectrometry, ANALYTICAL CHEMISTRY,2019, 91(13), 8199-8206.
9、Wang, R(Wang, Rong)[1,2] ;Liu, YF(Liu, Yanfang)[1,3] ;Zhou, H(Zhou, Han)[1] ;Chen, Y(Chen, Yue)[4] ;Wang, JX(Wang, Jixia)[1] ;Zhang, XL(Zhang, Xiuli)[5] ;Yu, RT(Yu, Ruitao)[3] ;Liang, XM(Liang, Xinmiao)[1] Integration of micro-fractionation, high-performance liquid chromatography-ultraviolet detector-charged aerosol detector-mass spectrometry analysis and cellular dynamic mass redistribution assay to accelerate alkaloid drug discovery. Journal of chromatography. A,2018,1616:DOI:10.1016/j.chroma.2019.460779
