陈洋，博士，副研究员
本草物质科学研究室/中药科学研究中心
电话：0411-8437
邮箱：chenyang2808@dicp.ac.cn
学习和工作经历：
2021.01 -今 中国科学院大连化学物理研究所，副研究员
2017.04 - 2020.11 美国国立卫生研究院，博士后
2018.09 - 2019.09 美国辛辛那提大学，博士后
2013.08 - 2017.06 中山大学肿瘤防治中心，基础医学，理学博士
2010.09 - 2013.06 东南大学，病理与病理生理学，医学硕士
2006.09 - 2010.07 江西中医药大学，生物科学，理学学士
研究方向：
1.重大疾病关键蛋白的作用机理研究
2.生物活性小分子的发现及药理学研究
代表性成果：
1、Rebuilding the lid region from conformational and dynamic features to engineering applications of lipase in foods : Current status and future prospects , Compr . Rev . Food Sci . Food Saf .(2022) . Co-corresponding author .
2、Prefused lysosomes cluster on autophagosome regulated by VAMP8 , Cell Death Dis . (2021) . 3rdauthor .
3、Structural and functional characterization of multiple myeloma associated cytoplasmic poly(A) polymerase FAM46C , Cancer Communications(2021) . 4thauthor .
4、Nanoscale Monitoring of Mitochondria and Lysosomes Interactions for Drug Screening and Discovery Strategies , Nano Res . (2019) . 4thauthor .
5、Molecular architecture of a cylindrical self-assembly at human centrosomes . Nat . Commun . (2019) , 3rdauthor .
6、Conformational dynamics of dynamin-like MxA revealed by single-molecule FRET , Nat . Commun . (2017) . 1stauthor .
7、MFN1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion,Nature(2017) . 3rdauthor .
8、Structural analysis of tumor-related single amino acid mutations in human MxA protein,Cancer Communications(2015) . 2ndauthor .
9、Cytoplasmic retention of a nucleocytoplasmic protein TBC1D3 by microtubule network is required for enhanced EGFR signaling , PLOS ONE(2014) . 4thauthor .
